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Malabsorption disorders : Patients with conditions like Crohns disease, celiac disease, or pernicious anemia that affect the absorption of nutrients may require more frequent injections, approximately every 4-8 weeks

IV therapy takes longer (3045 minutes) and provides a broader mix of nutrients through an IV drip

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Annual monitoring should include checking serum B12 levels and, if needed, MMA and homocysteine levels