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Semax has been shown in some studies to influence neurotrophic factors such as BDNF upregulation and other pathways involved in neuroprotection and cognitive processes

STAT3 activation is essential for tubulogenesis (Boccaccio et al., 1998)

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44 Notably, increased tumor blood volume is strongly associated with an unmethylated MGMT status, further reinforcing the role of imaging biomarkers in guiding treatment response and prognosis