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Description

A heterozygous mutation of DAO has been shown to segregate with the ALS phenotype in a large family with hereditary ALS (Mitchell et al., 2010)

SAM originated from methionine cycle in which 5-methyl THF transfers methyl groups to homocysteine in a reaction catalyzed by methionine synthase to produce methionine

Participants administered a mean chlorpromazine equivalent dose of 592.84 164.90 mg/day and a lorazepam equivalent dose of 1.58 0.70 mg/day

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