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Cystic fibrosis and cholestatic liver disease are also implicated in vitamin E deficiency with ocular findings largely revealing a decrease of the ERG b-wave, abnormalities of eye movement, and retinal degenerative changes (Alvarez et al., 1983)

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B6 also plays an important role in immune functions and is also a bio-marker of inflammation with its down-regulation being associated with severe inflammation (16)

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