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(Deficiencies in these vitamins can lead to various health issues, such as fatigue, weakness, anemia, nerve damage, skin disorders and cognitive problems.) Energy production- B vitamins are essential for converting carbohydrates, fats, and proteins into energy

Increased GST and/or GT tumor expression, generally considered as a bad prognosis marker (associated with drug resistance and disease progression), and could potentially be used as a predictive marker, allowing doctors, after biopsy, to identify which patients will respond best to GST or GT-activated prodrugs

This process regulates the miR-770-3p/triggering receptor expressed on myeloid cells 2 (TREM2) axis, thereby promoting microglial transition from the pro-inflammatory M1 to the anti-inflammatory M2 phenotype, which alleviates cognitive impairment and neuronal damage in AD mouse models [191]

Filtering of quantifiable proteins and missing values imputation were done as in the discovery untargeted analysis

Standard treatment approaches include rest, ice, anti-inflammatory medications, physical therapy, bracing, and in some cases cortisone injections