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Together, these actions are thought to produce more pronounced weight loss and metabolic improvements than dual or single receptor agonists

Sterile 0.9% saline is appropriate where a physiological salt concentration is required by the experimental design

What they found: Oral AOD-9604 reduced body fat by 18 to 22 % vs placebo, comparable to injection administration No changes in total body weight (because lean mass rose slightly) Decrease in plasma triglycerides by 30 % Decrease in resting free fatty acids (paradoxically, mobilization of fat from depots into oxidation) No GI side effects Why it matters: It suggested that AOD-9604 could work orally , a rare property for a peptide

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