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Tirzepatide for reduction of morbidity and mortality in adults with obesity: rationale and design of the SURMOUNT-MMO trial

Karaa M, Kili E, Yazici B, Demir S, Torre J de la

Tissue histology and immunostaining Colon Swiss rolls soaked in 4% paraformaldehyde solution were dehydrated, embedded in paraffin, cut into 4-m-thick sections, and stained with haematoxylin and eosin (H&E) using standard procedures

When mammalian cells experience irreversible disruptions in their internal or external milieu, they can initiate several signal transduction cascades that ultimately result in cell death (Kayagaki et al., 2024

Moreover, 308 subjects with type 1 diabetes maintained normal renal function, whose subsequent detection of metabolites displayed that the SCFAs are enriched in the majority of patients (at least 80%) (132)