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In phase 3 trial (VANGUARD), 65 eligible patients were randomized into two groups: 39 received the drug as a 400 mg subcutaneous loading dose followed by five additional monthly 200 mg subcutaneous injections, whereas 25 patients received volume-matched placebo

[DOI] [PubMed] [Google Scholar] 12.Cordiano R., Di Gioacchino M., Mangifesta R., Panzera C., Gangemi S., Minciullo P.L

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The GSH response with repeated exposures is also very interesting since the level of GSH in the ELF is established at a lower, but still protective level within the first 3 days of CS exposure

2018;13(7):e0199373