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As anticipated, the dissection of apparent equilibria into elementary redox ones in biological thiol-disulfide systems reveals significant differences between reactions of apparently highly similar, covalently identical reactants, improving thus our understanding of redox homeostasis and providing new means to influence it

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Furthermore, while the presence of do not eat me signals, such as CD47 and PD-L1, is known to regulate phagocytosis in other cellular contexts, their existence and role in ferroptotic cells remain largely uncharacterized

10.1016/j.drudis.2009.10.009 150 WangC.LiuY.FanY.LiX