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On the other hand, the redox state disequilibrium or down modulation of GSH made these MDR cells more sensitive to chemotherapy [9]

Ultimately, advancing from laboratory studies to well-designed clinical trials will determine whether GSH-responsive nanomedicine can fulfill its potential in precision oncology

Anisimov VN, Khavinson VK, Popovich IG, Zabezhinski MA, Alimova IN, Rosenfeld SV, Baturin DA, Semenchenko AV, Yashin AI

For readers interested in the broader regenerative-signaling case, the sites discussion of GHK-Cus role in tissue-repair signaling catalogs that literature in more depth