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Data availability The proteomic datasets generated during this study have been deposited to the ProteomeXchange Consortium ( via the PRIDE repository (identifier: PXD056759)

Lymphatic dysfunction exacerbates cutaneous tumorigenesis and psoriasis-like skin inflammation through accumulation of inflammatory cytokines

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Water, Glycerin, Methylpropanediol, Acrylates/Ethylhexyl Acrylate Copolymer, Niacinamide, Chondrus Crispus Powder, 1,2- Hexanediol, Butylene Glycol, Betaine, Ceratonia Siliqua (Carob) Gum, Hydroxyacetophenone, Allantoin, Glucomannan, Xanthan Gum, Laureth-21, Panthenol, Polyglyceryl-10 Laurate, Propanediol, Cellulose Gum, Cyamopsis Tetragonoloba (Guar) Gum, Fragrance(Parfum), Potassium Chloride, Dextrin, Adenosine, Ethylhexylglycerin, Hydrolyzed Collagen, Cyanocobalamin, Ascorbic Acid, Sodium DNA, Tocopherol, Acetyl Hexapeptide-8, Ascorbic Acid Polypeptide, Acetyl Octapeptide-3, Acetyl Tetrapeptide-2, Acetyl Tetrapeptide-3, Acetyl Tetrapeptide-5, Acetyl Tetrapeptide-9, Carnosine, Copper Tripeptide-1, Nonapeptide-1, Palmitoyl Pentapeptide-4, Palmitoyl Tripeptide-1, Palmitoyl Tripeptide-5

Because traditional centrifugation-based methods are too slow to preserve ER metabolite content, we adapted an immunopurification strategy previously developed for other organelles 1315