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Description

PLoS One 11 (8), e0161074

These findings demonstrate that irisin confers neuroprotection in PD through multiple mechanisms, including the regulation of motor function, dopaminergic neuron survival, mitochondrial function, and neuroinflammation

For example, the chin area was always hyperactive and synkinetic, but showed a high degree of improvement even as the pharmacologic effect of BoNTA declined over time