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6 This study found an increased number of T cells in the olfactory epithelium as well as a decreased number of anti-inflammatory M2 macrophages, leading to heightened inflammation, which may explain prolonged anosmia in patients with long COVID

ROS are present in cells and tissues at low but measurable concentration which is determined by the balance between the rate of production versus the clearance by different antioxidant enzymes (SOD, glutathione peroxidase and catalase) and compounds (glutathione, ascorbate, -tocopherol, -carotene).12 A complex functional modulation of several proteins occurs upon cellular oxidative stress.13-15 In particular, this is accomplished through modification of proteins since several aminoacids, such as Tryptophan, Tyrosine, Histidine and particularly Cysteine, are direct targets of ROS.16 ROS-mediated protein modification can affect both protein structure and function and protein stability

The FAT and FATC domains modulate the activity of the kinase domain

suis is not able to utilize glucose for its main energy supply

H.ChoiE.-J.et al (2004)