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Since astrocytes are closely linked with the synapse, which receives signals from the pre-synaptic neuron and responds by releasing feedback signals, they play a crucial role in brain function in health and disease

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Concordance (shared diagnosis) of 90% of monozygotic (identical twins) and 10% of dizygotic (fraternal twins), published in the 1970 s, was initially used to justify an intensive focus on genetics to the exclusion of environmental influence [150]