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Sox2 induces glioblastoma cell stemness and tumor propagation by repressing TET2 and deregulating 5hmC and 5mC DNA modifications

Furthermore, elevated ammonia concentrations induce cytotoxic edema in astrocytes, initiating a cascade of oxidative stress responses within the brain parenchyma that ultimately lead to neuronal dysfunction and neurological impairment 1

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[DOI] [PubMed] [Google Scholar] 209.Ibrahimpasic T, Ghossein R, Carlson DL, Nixon I, Palmer FL, et al

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