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The membrane lipids, mainly phospholipids, containing polyunsaturated fatty acids are predominantly susceptible to peroxidation because abstraction from a methylene (-CH2-) group of a hydrogen atom, which contains only one electron, leaves at the back an unpaired electron on the carbon, -*CH-

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Back to Journals International Journal of Chronic Obstructive Pulmonary Disease Volume 20 Metabolic Regulation in Acute Respiratory Distress Syndrome: Implications for Inflammation and Oxidative Stress Received 15 August 2024 Accepted for publication 1 December 2024 Published 18 February 2025 Volume 2025:20 Pages 373388 DOI Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 2 Editor who approved publication: Professor Min Zhang Lixia Yue, Yihe Yan Department of Critical Care Medicine, Shaoxing Peoples Hospital, Shaoxing, Zhejiang, 312000, Peoples Republic of China Correspondence: Yihe Yan, Email [email protected] Abstract: Acute respiratory distress syndrome (ARDS) is a severe and life-threatening pulmonary condition characterized by intense inflammation and disrupted oxygen exchange, which can lead to multiorgan failure