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Coq, denotes yeast polypeptide

Thats where the newest treatment, Pegloticase, steps in

However, these florescent probes are susceptible to various drawbacks such as photo-bleaching and molecular leaching from the host, which may result in serious experimental artifacts 6,7,8,9

Instead, patient stratification, biomarker-guided dosing, and careful metabolic phenotyping are likely required to optimize therapeutic benefit while minimizing potential adverse or paradoxical effects