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Table 1 Key molecular regulators and pathways in ferroptosis

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Most solid tumors are plugged into the systemic circulation through the stroma , a mixture of non-malignant cells pertinent -but not limited- to the hosting tissue such as fibroblasts, nerve and immune cells, blood vessels, extracellular matrix proteins and adipocytes 20 , representing up to 90% of tumor mass 21

Fisher is the first that I know of to identify a deficiency in a specific complex in the electron transport chain