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N Engl J Med 376:20532064

For instance, for a collective of 24 neurologically healthy sample donors, a good, age-consistent BBB-integrity value of albumin quotient ( Q HSA ) of 5.25 10 3 , but higher Q -values for GPX ( Q GPX = 8.31 10 3 ) and TXNRD ( Q TXNRD = 21.34 10 3 ) were observed, demonstrating active transport into the brain-CSF compartment (Solovyev et al., 2013)

Effect of supplemental oral L-arginine on exercise capacity in patients with stable angina pectoris

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In vehicle-treated rats, fentanyl elicited (1) an increase in TFL, (2) decreases in pH, pO 2 and sO 2 and increases in pCO 2 (all indicative of ventilatory depression), (3) an increase in Alveolar-arterial gradient (indicative of a mismatch in ventilation-perfusion in the lungs), and (4) changes in ventilatory parameters such as a reduction in tidal volume, that were indicative of pronounced ventilatory depression