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This innovative nanosystem encapsulates DNAzymes, a single-stranded catalytic DNA molecule renowned for its diverse biological functionalities, including gene silencing, the selective cleavage of specific mRNA sequences, and the facilitation of various chemical transformations through catalytic activity 38,39,40

However, the effect is limited when used externally alone

Metallothionein: a protein for metal elimination MTs represent a family of ubiquitous, low-molecular-weight, metal-binding proteins that have a molecular mass of less than 7,000 Daltons, containing approximately 33-percent cysteine residues [94]

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For example, in a Parkinsons disease mouse model treated with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), lanosterol levels were reduced by approximately 50% in the nigrostriatal region, a key site of dopaminergic neuron loss