doi: 10.1111/acel.13832
In a study using microRNA (miR)-6077-targeted inhibition of Keap1 expression, the resulting initiation of antioxidant genes by Nrf2 was found to be a key factor in the inhibition of ferroptosis and generating cisplatin resistance in LUAD
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Plant Physiol 162:20152027
However, a better understanding of the cellular and molecular mechanisms that are involved in the underlying inflammatory and destructive processes has revealed several new targets for which drugs are now in development, and the prospects for finding new treatments are good
