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1991 Aug;30(32):804551

Bouchareb A, Le Cam A, Montfort J, Gay S, Nguyen T, Bobe J, et al

Warning: Vitamin B12 1mg/ml must not be used in newborn babies, especially in those showing signs of immaturity, due to the benzyl alcohol content

NB and NMA provided and analyzed the Saudi cohort

This review attempts to provide some mechanistic insight (Figures 13) into how the bi-directional network between the gut microbiota and the brain can not only protect but also trigger and aid chronic gut inflammation, promote a global pro-inflammatory state, modify and contribute to protein misfolding processes, dysregulate the autophagic-lysosomal protein clearance mechanism, differentiate T-cell subsets to facilitate a deleterious autoimmune response, and finally modulate immune recruitment and BBB status