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not directly guided by the underlying DNA sequence) perturbations in chromatin states, it is unclear how they alone can result in the activation of specific metastatic transcriptional programmes

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(117) found that the relative abundance of p-cresol-producing bacteria was significantly increased in ESRD patients, with markedly elevated serum pCS concentrations

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This study highlights the potential of enzyme-mimicking nanomaterials in replicating multifunctional enzyme activity and supports material-based strategies for targeting cancer metabolism