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All tumor experiments were conducted according to the VAI IACUC-approved protocols in conjunction with the VAI Vivarium (RRID:SCR_023211)

Fragmentation was performed by divalent cations in NEBNext First Strand Synthesis Reaction Buffer

Beyond that, there are several supplements with varying degrees of evidence supporting their use

In theory, these opposing effects on glucose metabolism could partially offset one another, but the net result in any individual patient is difficult to predict without close clinical monitoring

In keeping with this notion, older studies of children with asthma have observed alternations in tryptophan metabolism that were reversed by vitamin B 6 supplementation (50, 51)