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FUN14 domain-containing protein 1 (FUNDC1), a mitophagy receptor highly expressed in the liver tissues of patients suffering from liver fibrotic injury as well as carbon tetrachloride-challenged mice, has been identified as a culprit in eliciting liver cell ferroptosis

Vitamin B12 exists in various chemical forms, and apart from hydroxocobalamin, three other essential types of vitamin B12 are commonly known: Methylcobalamin

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Given the broad and orthogonal substrate scopes established for Cp1B and Cp1D, a library of more than 1,200 E-64 analogs can be generated in one-pot reactions