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Early haematological response begins with reticulocytosis (increased production of immature red blood cells) typically by day 3-4 of treatment , particularly with injectable forms, though the full resolution of symptoms may take several weeks to months

"BSH Cobalamin and Folate guidelines" published 2014 NICE published a new B12 deficiency guideline in 2024 I have some doubts about this guideline but I think it's worth reading

Various studies have attempted to show that vitamin C supplementation and deficiency can affect a variety of autoimmune conditions including rheumatoid arthritis and type 1 diabetes mellitus