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While many side effects are manageable, certain symptoms require prompt medical evaluation: Severe or persistent abdominal pain Signs of pancreatitis, such as nausea, vomiting, and severe stomach pain Symptoms of hypoglycemia, especially if frequent or severe Allergic reactions, including rash, swelling, or difficulty breathing Persistent diarrhea or dehydration If you experience any of these, seek medical advice immediately

doi: 10.1016/j.molmet.2020.101131 24 BoroughsLKDeBerardinisRJ

BaP is a carcinogen and can cause epigenetic changes such as DNA methylation and histone acetylation [15], in addition, BaP can affect DNA methylation and demethylation, the most important part of epigenetics, by influencing DNMTs and thus DNA methylation [77, 152]

Taoka Y, Naruo M, Koyanagi E, Urakado M, Inoue M

Continuing the protocol through at least four weeks before judging effectiveness remains important