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In contrast to the canonical pathway, the non-canonical NF-B activation does not involve IB degradation but is dependent on the p100 (NF-B2) precursor protein

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However, as the development and testing of remyelination-based therapies requires effective model systems with sustained demyelination and lack of complete endogenous remyelination, we conclude that 1 mM CPZ treatment of brain slice cultures is not a viable ex vivo model for these studies, however, could prove to be useful in acute demyelination studies, pending further characterization

For example, a 10mg vial reconstituted with 1.7mL gives you 5.88mg/mL