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Targeting ferroptosis may offer valuable insights for developing of TBI therapies

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Conversely, the release of inflammatory cytokines promotes the progression of ferroptotic cell death, such as the inhibition of GPX4 expression in tumour necrosis factor--treated cells (Fig

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All experiments were carried out in compliance with the National Institutes of Health (NIH) guidelines for the care and use of laboratory animals and were previously approved by the Ethics Committee on the Use of Animals of the Institute of Biomedical Sciences at the University of So Paulo