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The gene expression Omnibus database

In the in vivo study, diabetes was chemically induced in rats

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A proteomic analysis revealed that cardiac ischemia-reperfusion injury causes Kcro of proteins associated with cardiomyocyte contractility, resulting in the disruption of cardiomyocyte mitochondrial, sarcomere architecture, and gap junction, as well as the induction of cardiomyocyte apoptosis