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Donghui Na, Zechen Zhang, Junyan Gao, Ying Guo, Guohui Zhang and Jiming Kong prepared the figures, wrote, corrected, amended, and approved the final edition of the manuscript

Therefore, Met utilization may alter the DNA and histones methylation level, influencing the overall abundance of mRNA and proteins, and, consequently, the upcoming phenotype

L., Berens, K

Prediagnostic alterations in circulating bile acid profiles in the development of hepatocellular carcinoma

Real-Time PCR To quantify mRNA levels of OA and apoptosis-related gene expression, total RNA was extracted from the cells for in vitro and cartilage for in vivo according to the manufacturers instructions (iNtRON Biotechnology, South Korea)