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So RBC aggregation is accepted as a significant determinant of resistance in venules

Bell MR, et al

LOXs, a group of iron-containing enzymes, are responsible for catalyzing the PUFAs (with a 1,4- cis, cis pentadiene system) oxidation through stereo-specific peroxidation to produce corresponding fatty acid hydroperoxides (Kuhn et al., 2018)