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While TG serves as a physiological adaptation to excess energy intake, chronic overconsumption of SFAs disrupts lipid homeostasis, leading to ectopic TG accumulation in non-adipose tissues, a phenomenon known as lipotoxicity ( Exposure to SFAs drives macrophage polarization toward a pro-inflammatory M1-like phenotype

References Lpez-Otn, C., Blasco, M

The same ultrasound machine was used at initial presentation and in the follow-up examinations (Philips Affinity 70 G), and the ultrasound examination was always performed by the same doctor

Yet, common polymorphisms in genes involved in choline or folate metabolism alter ones susceptibility to choline deficiency and thus may affect dietary requirements for choline (see Deficiency) (18, 20, 33, 34)

Mitochondrial Dysfunction and Reactive Oxygen Species in Excitotoxicity and Apoptosis: Implications for the Pathogenesis of Neurodegenerative Diseases