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Journal of Clinical Investigation 2006;116:344-356

doi: 10.1016/j.freeradbiomed.2013.03.022 155

Int J Adv Med 6:580584

doi: 10.1016/j.freeradbiomed.2022.05.024 97 GuoJZhouYLiuDWangMWuYTangDet al

It is reported that the cystine-glutamate antiporter-xCT is suppressed on exposure to sorafenib, leading to the accumulation of ROS and GSH depletion [17]