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Therefore, arginine metabolism and subsequent polyamine biosynthesis play pivotal roles in regulating CD4 + T cell differentiation in disease settings

Western blot results revealed an augmented expression of gankyrin in several TNBC cell lines, including MDA-MB-231, HCC-1937, MDA-MB-468, BT-20, Hs578T, compared to normal cell MCF-10A (Fig

Several CoQ biosynthesis genes have been implicated in epilepsy including COQ1-PDSS2 , COQ2 , COQ4 , COQ5 , COQ6 , COQ8-ADCK3 , COQ8-ADCK4 , and COQ9 , with COQ2 , COQ4 , and COQ8-ADCK3 mutations being more frequently associated with seizures (124)

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