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doi: 10.3389/fphar.2012.00060 50 GaoKWangCRJiangFWongAYSuNJiangJHet al

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These iron enzymes are located in essentially every subcellular compartment

Conjugation reactions usually involve metabolite activation by a highenergy intermediate and have been classified into two general types: type I (e.g., glucuronidation and sulfonation), in which an activated conjugating agent combines with substrate to yield the conjugated product, and type II (e.g., amino acid conjugation), in which the substrate is activated and then combined with an amino acid to yield a conjugated product (Hodgson, 2004)

The use of vegetable juices, citrus juices, bananas, melons, and other fruits and vegetables may need to be increased