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Cytoplasmic serine hydroxymethyltransferase mediates competition between folate-dependent deoxyribonucleotide and S-adenosylmethionine biosyntheses

The findings of some of the clinical trials in which lipoic acid administration has been tested in diabetic patients during the last 10 years are summarized

Quintanilla-Licea R, Vargas-Villarreal J, Verde-Star MJ, Rivas-Galindo VM, Torres-Hernndez D (2020) Antiprotozoal activity against Entamoeba histolytica of flavonoids isolated from Lippia graveolens Kunth

Cevimeline activates receptors more selectively, but has similar side effects

In PD models, the use of dependent sodium channel blockers reduces glutamatergic hyperactivity and inhibits abnormal glutamate release, suggesting that amino acid metabolism disturbances may contribute to neurotoxicity and oxidative toxicity, ultimately resulting in dopaminergic neuron death [85]