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Glycosphingolipids Prevent APAP and HMG-CoA Reductase Inhibitors-mediated Liver Damage: A Novel Method for Safer Drug Formulation that Prevents Drug-induced Liver Injury

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Recent studies indicate that NRF2 regulates hundreds of genes related to redox homeostasis and other physiological processes, and that dysregulation of NRF2-regulated genes provides a logical explanation for direct and indirect connections between oxidant stress and more than 200 human diseases [20]

doi: 10.3390/biomedicines8110454 22