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Their characterization by electrophysiological approaches revealed that they are mostly closed under basal conditions and activated by different stimuli that are also known to induce eryptosis: ROS, exposure to high extracellular osmolarity, or removal of extracellular Cl - and isosmotic replacement with gluconate activate the channel [98] and trigger eryptosis [90]

Oncogene 34 , 31883198 (2015)

NAD+ metabolism enzyme NNMT in cancer-associated fibroblasts drives immune evasion in urothelial carcinoma by elevating PD-L1 N-glycosylation

Oxidative stress and ageing: is ageing a cysteine deficiency syndrome

doi: 10.1177/1177272716689818