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Effects of bumetanide on neurodevelopmental impairments in patients with tuberous sclerosis complex: an open-label pilot study

What we can say with confidence is that many of our patients report meaningful benefits, including increased energy, improved workout recovery, and enhanced results when lipo shots are combined with a structured diet and exercise plan

Although a significant proportion of cases were not genetically characterized, highlighting a gap in current diagnostic practices, most of the AMN variants were homozygous, aligning with past studies that identified this gene as a major factor for IGS development [32,33,34]

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