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Grce des astringents et des ingrdients naturels, les impurets de surface sont limines sans dcaper la peau

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Samples were reconstituted in 90 l of 50% acetonitrile (Fisher Scientific, A955) and transferred to glass vials for LCMS analysis

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When a leaving group is installed at the propargyl position of COT, this intermediate undergoes rapid 1,4-elimination, releasing the payload and generating a nitroneoctenea bioorthogonal bond-cleavage reaction with fast kinetics and near-quantitative efficiency (Fig