We hypothesized that high 15LO1, PEBP1, and GPX4 activity drives abnormal asthmatic redox biology, evidenced by lower bronchoalveolar lavage (BAL) fluid and intraepithelial cell GSH:oxidized GSH (GSSG) ratios, to enhance type 2 (T2) inflammatory responses
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Rapamycin influences the mTOR pathway to potentially boost collagen production, strengthening skin foundation for a more youthful appearance
Shaw K, Williams SP, Patrick M, ValenciaPrado M, Durkin MS, Howerton EM, Ladd-Acosta CM, Pas ET, Bakian AV, Bartholomew P, Nieves-Muoz N, Sidwell K, Alford A, Bilder DA, DiRienzo M, Fitzgerald RT, Furnier SM, Hudson A, Pokoski OM, Shea L, Tinker SC, Warren Z, Zahorodny W, Agosto-Rosa H, Anbar J, Chvez K, Esler A, Forkner A, Grzybowski A, Agib AH, Hallas L, Lopez M, Magaa S, Nguyen RHN, Parker J, Pierce K, Protho T, Torres H, Vanegas SB, Vehorn A, Zhang M, Andrews J, Greer FL, HallLande J, McArthur D, Mitamura M, Montes A, Pettygrove S, Shenouda J, Skowyra C, Washington A, Maenner MJ (2025) Prevalence and early identification of autism spectrum disorder among children aged 4 and 8 yearsautism and developmental disabilities monitoring network, 16 sites, United States, 2022
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Research published in Cell Metabolism demonstrates that GIP receptor activation enhances nutrient partitioning, meaning the body becomes more efficient at directing calories toward metabolically active tissue rather than fat stores