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In a study, participants with early AMD who consumed 8 mg per day of dietary zeaxanthin for one year improved their night driving and their visual acuity improved an average of 1.5 lines on an eye chart

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However, titration with His, which forms 2: 1 complex in our experimental conditions and leads to fast demetallation of CuHSA, yielded K D equal to 34.7 4.5 fM (50 mM Hepes, 50 mM NaCl at pH 7.4)