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Among the mechanisms are a decrease in oxidative stress impairment, and modulation of protein levels linked with the mitochondrial apoptotic pathway and its inhibition

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Of the four known SDH assembly factors, only mutations in SDHAF1 have been linked to complex II deficiency

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Broccoli and other cruciferous vegetables contain sulforaphane, an isothiocyanate that has been shown to be a potent inducer of phase II detoxification enzymes and a modulator of epigenetic control

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