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Symptoms and pregnancy outcomes associated with extreme weight loss among women with hyperemesis gravidarum

Iliceto S, Scrutinio D, Bruzzi P, et al

Fluctuations in intraocular pressure (IOP), insufficient blood supply to the optic nerve, malnutrition, trauma, hypoxia-induced inflammatory responses, and degeneration of RGCs are the basic factors for its onset (123), among which the increase in pathological intraocular pressure (ph-IOP) and the death of RGCs are the key factors (124)

2 followed doxorubicin treatment at 8 weeks of age as described in the NMN and chemotherapy treatment protocol above, while for the breeding trial in cisplatin-treated mice (Fig