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The inhibition of transcription factors and enzymes involved in lipid synthesis is a remarkable aspect of gene expression, including fatty acid synthase, stearoyl-CoA desaturase-1, and sterol regulatory element-binding protein-1c [65]

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The meal test also revealed large variability in the pharmacokinetic profile, which resulted in hyperglycemic and hypoglycemic events

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To bridge these gaps, nextgeneration approaches are under investigation: ADSCderived exosomes as cellfree therapeutics

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meningitidis (NME 8013) in a model with the Calu3 cell line, used to model the human airway epithelium, grown in air interface culture (cells grown with the apical domain facing air) to stimulate mucus production ( S

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Nat Commun 10(1):1617

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