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High levels of amino acid in the blood increases the chance of heart disease, sudden death of brain cells, Dementia, and porous bones.The deficiency of B12 in the body may result in pernicious anemia , low red blood cells in the body, tiredness, breathlessness, unusual fast beating of the heart

Dr Hanley reports personal fees from Neurotrope, Neurelis, and medico-legal, outside the submitted work

HPLC fractionation The tryptic peptides were fractionated by high pH reverse-phase HPLC using Agilent 300 Extend C18 (5 m particles, 4.6 mm ID, 250 mm length)

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