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Overall, we evaluate whether these disease-modifying emerging therapeutics hold promise as interventions that may be able to reverse or halt AD progression

For example, ROS produced by neutrophils or tumour cells can be transferred to T cells and cause OS, thereby causing hyporeactivity of T cells in cancer patients (185)

In addition, the day before running the assay, the Seahorse XF Sensor Cartridge was hydrated with sterile water followed by the calibration step (200 L per well of Seahorse XF Calibrant Solution) the day of the experiment in a non-CO 2 37 C incubator

Ltd, Tokyo, Japan) equipped with a Peltier-controlled cell holder (model PTC-517, JASCO)