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For instance, network pharmacology and metabolomics can be leveraged to map the multi-target synergistic networks of these natural derivatives against the highly heterogeneous pathophysiology of sepsis

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doi: 10.1002/jbm.a.34509 196 PreviteraMLSenguptaA

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MP infection causes a significant decrease in serum TGF-1 levels in children, and weakens the ability to induce and activate CD4+CD25+Treg, leading to a decrease in immune suppression function and an increase in immune response, resulting in thrombocytopenia (146)