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doi: 10.1158/0008-5472.CAN-07-2310

Cellular stress and AMPK activation as a common mechanism of action linking the effects of metformin and diverse compounds that alleviate accelerated aging defects in Hutchinson-Gilford progeria syndrome

Conclusion: This consensus underscores the role of NAC in chronic respiratory diseases beyond its mucolytic properties and reiterates that NACs antioxidant, anti-inflammatory, immunomodulatory and anti-biofilm properties provide significant clinical utility